I have non-stop fasciculations in both calf muscles, and have done since a month or so after my first tingling symptoms a few years ago. The calf fasciculations are permanent with me. I have also had eyelid twitches, non stop for three months, until my neuro gave me botox injections. I still have occasional bouts of eyelid twitching, but, fingers cross, tends to subside.

My understanding of twitching/fasciculations is that it could be a sign of motor neuron issues but can also be an extension of sensory problems sending out the wrong signals.

I take heart in the fact that people with benign fasciculation syndrome (BFS) have precisely the same symptoms without concern or alarm--this makes me think that it doesn't take a lot of nerve damage to cause twitching.