Hello Alexia,

Welcome to NeuroTalk. Despite the thread being old, I received notification of your response thanks to having email notifications being enabled on the thread.

I'm happy you posted. I feel rather alone with this gene mutation. I assume you have only one copy and not two? Having two copies is much more problematic.

Since making sure I supplement with biotin everyday, I have not been hypoglycemic once. It was definitely causing me metabolism problems. Unfortunately, I've seen no improvement with my ability to metabolize alcohol, nor has it improved my neuropathy problems.

The latter, however, I've just recently discovered are associated with histamine overload, which is a whole nightmare in itself.

Have you had your biotinidase enzyme levels tested?

Jane