OP: I went thru 10 yrs on SSRI's and all along I believed it was thyroid issues and finally a good ole doc in my life gave me a script of Armour thyroid and that long stretch of depression lifted fast, never to return and I've been taking a desiccated thyroid support for 18 wonderful yrs. Young people can have thyroid issues as well so I'm just saying. I realize your issues are very different but we all have thyroids.... And when I was going thru my initial treatments and male friend in my world was also in this arena. So men do have thyroid issues as well.

Finding a good doc to investigate this issue is key.

5HTP has not really worked in my life but since I've been taking L Tryptophan with my sleep stuff my sleep is better than ever.....

Every body is different.