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Old 08-15-2021, 09:43 PM
jeffreyn jeffreyn is offline
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Join Date: Apr 2016
Location: Australia
Posts: 352
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jeffreyn jeffreyn is offline
Member
 
Join Date: Apr 2016
Location: Australia
Posts: 352
8 yr Member
Default Formal announcement of completion of the Phase 1 trial

This announcement has already been covered in another thread by ashleyk.
International Stem Cell Corporation

I'm covering it here as well to join it up with the many previous posts on this topic.

Some good news is that the results of the Phase 1 trial show safety, and possible efficacy.

Some bad news is that no plans were mentioned for a Phase 2 trial, only that "Patients will continue to be evaluated every six months for another five years in the study’s extension phase."

PNT article:
Parkinson's Stem Cell Therapy Shows Safety, Early Efficacy in Small Trial

Press release:
International Stem Cell Corporation Announces Successful Completion of Its Phase 1 Clinical Trial in Parkinson's Disease

"The quality of life of the patients as measured by the Parkinson's Disease Quality of Life Score-39 (PDQ-39) Summary Index, improved 43% for the second cohort at twelve months post-transplantation. This improved to a 45% better score in cohort 2 at 48 months."

I think there is a typo there, in that "48 months" should probably be "24 months". It really can't be 48 months, since cohort 2 has only been observed for 36 months.
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