I have LAS and learned about FYCOMPA thru this journal article - contact Berhard J. Steinhoff
The Germans have some of the most experience with FYCOMPA (Peramapanel).
I've been using 2mg/day and it has made a HUGE difference in my life.
Good Luck!
James Casselman
Quote:
2016.05.001
PMCID: PMC4939387
PMID: 27437182
Add-on perampanel in Lance–Adams syndrome
Bernhard J. Steinhoff,⁎ Matthias Bacher, Christoph Kurth, Anke M. Staack, and Reinhold Kornmeier
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Abstract
Perampanel (PER) is the first-in-class selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist that has been licensed and marketed as antiepileptic drug (AED) indicated for patients with partial-onset and primary generalized tonic–clonic seizures. A positive effect was reported in some patients with epileptic myoclonic jerks in idiopathic generalized epilepsy and in progressive myoclonic epilepsy.
We treated a male patient with posthypoxic nonepileptic myoclonus (Lance–Adams syndrome) with add-on PER and achieved an almost complete cessation of jerks. This effect was reproducible and, therefore, we suggest that it might be worth trying PER in comparable cases.
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