hello Razzle51, I have had idiopathic PN for over 7 years. During this time my primary symptoms were loss of balance, numbness in feet and fingers and also in arms and legs plus tingling and sunburning in arms and legs with occasional sharp pain in toes. I moved from alpha Lipoic acid to R-Lipoic acid (300mg daily) because I felt that alpha-lipoic acid was not working but neither did R-Lipoic acid. For several weeks I even had IV infusions of alpha-lipoic acid. I never felt a benefit and after 5 years I discontinued this supplement without any effects.