I really don't know that much about meds but was eductaed more at the pain clinic program where many were overusers though I am not at all myself. During this 6 months of pain for a few months I was on vicadin and when I quit completly before I went about a month ago I had no craving or issues. I think it depends on the person. I did notice from the people who had issues with prescription drug and overuse they also used other drugs that were not prescription. I may be wrong and I'm sure there are some who just overuse the prescription but I did see a trend of both drugs overused. For a person who the prescription drugs seem to not work for other then the bad side effects I'm in a little different spot. In general I do think its a combo of things to work overall. So maybe the meds,supplements,therapy,pt so on.