Hi Vision Quest,

Thanks for sharing your story. You've had it really bad and I feel for you. I love your sense of humour.

Just some thoughts ... Vitamin B6 is water-soluble as you know. It has a half-life of 25–33 days and accumulates in the body where it is stored in muscle, plasma, the liver, red blood cells and bound to proteins in tissues. In high doses it is neurotoxic.

Megavitamin-B6 syndrome is predominately a large fibre polyneuropathy. This is consistent with your EMG and some of your symptoms.

It can take weeks to months to rid your body of B6 from high accumulation. The prognosis is good and symptoms greatly recede for the vast majority of people.

I believe coffee and and an Inulin supplement can help with ridding the body of B6. Inulin is a prebiotic. I take it myself following microbiome analysis. It may help you.

Please keep us updated.

Best wishes,

Atty