Sheesh, I know what you're saying. It's all so frustrating.

Keep in mind that our Docs are also frustrated, because they can't cure us and the choice of MS Meds given to them are only possible bandaids, which may or may not slow the MS progression.
The fact is that these MSMDs do not help all PwMS nor all types of MS, so it's a crapshoot and if one or all of them is not doing the job and hurting your quality of life, it just isn't worth it, IMO, to keep on shooting yourself up with it.
Keep asking questions (whining)...A squeaky door usually gets oiled first.

It's your life and your illness and they are supposed to be helping you.....not the other way around.