Thread: Oats
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Old 09-25-2006, 09:55 PM
annelb annelb is offline
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Join Date: Aug 2006
Location: Arkansas
Posts: 239
15 yr Member
annelb annelb is offline
Member
 
Join Date: Aug 2006
Location: Arkansas
Posts: 239
15 yr Member
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Back to oats for a minute. Sorry, I know the subject has changed but I have not had a chance to post earlier.

This study was done with oats that were tested for possible gluten. IMHO, caution is needed when adding oats to the diet.

http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
Quote:
Oats induced villous atrophy in coeliac disease.

* Lundin KE,
* Nilsen EM,
* Scott HG,
* Loberg EM,
* Gjoen A,
* Bratlie J,
* Skar V,
* Mendez E,
* Lovik A,
* Kett K.

Department of Medicine, Rikshospitalet, Oslo, Norway. knut.lundin@rikshospitalet.no

The current trend is to allow coeliac disease (CD) patients to introduce oats to their gluten free diet. We sought further data from the clinical setting with regards to oats consumption by coeliac patients. Several oat products were tested for wheat contamination using a commercial enzyme linked immunoassay (ELISA) kit, and six samples were examined by an ELISA using a cocktail of monoclonal antibodies, mass spectrometry, and western blot analysis. Nineteen adult CD patients on a gluten free diet were challenged with 50 g of oats per day for 12 weeks. Serological testing and gastroduodenoscopy was performed before and after the challenge. Biopsies were scored histologically and levels of mRNA specific for interferon gamma were determined by reverse transcription-polymerase chain reaction analysis. Oats were well tolerated by most patients but several reported initial abdominal discomfort and bloating. One of the patients developed partial villous atrophy and a rash during the first oats challenge. She subsequently improved on an oats free diet but developed subtotal villous atrophy and dramatic dermatitis during a second challenge. Five of the patients showed positive levels of interferon gamma mRNA after challenge. Some concerns therefore remain with respect to the safety of oats for coeliacs.

PMID: 14570737 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
Quote:
CONCLUSIONS: We conclude that some celiac disease patients have avenin-reactive mucosal T-cells that can cause mucosal inflammation. Oat intolerance may be a reason for villous atrophy and inflammation in patients with celiac disease who are eating oats but otherwise are adhering to a strict gluten-free diet. Clinical follow-up of celiac disease patients eating oats is advisable.

PMID: 15526039 [PubMed - indexed for MEDLINE]
Anne
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