Medical News Today article...
Neurology / Neuroscience News
Article Date: 07 Aug 2007
http://www.medicalnewstoday.com/articles/78872.php
Deep Brain Stimulation And Tourette Syndrome
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Still considered experimental, the procedure used-Deep Brain Stimulation (DBS)-involves the implantation of electrodes in the brain that are stimulated by a surgically implanted pulse generator in the upper chest. Several studies have shown that this surgical intervention may aid in the amelioration of involuntary movements in patients with Parkinson's Disease and Essential Tremor. More recent studies have shown promise for other disorders including Dystonia.
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Early experience with DBS for tics in TS has been mixed. While some individuals have experienced a reduction in symptoms, others have not. There is no long-term follow-up yet to indicate whether or not symptoms will return at some point. It should be understood that when undergoing this procedure, there might be serious risks involved that could include cerebral bleeding and infection.
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Only rigorous, methodologically sound scientific study of DBS will provide the answers we seek.
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TSA-USA Statement: Deep Brain Stimulation and Tourette Syndrome
Following is a statement from TSA Medical and Scientific Advisors.
http://www.tsa-usa.org/news/DBSStatement.htm
(I notice this Statement has been updated 8/2007)
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PubMed Abstract
Mov Disord. 2006 Nov;21(11):1831-8.
Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome.
Mink JW, Walkup J, Frey KA, Como P, Cath D, Delong MR, Erenberg G, Jankovic J, Juncos J, Leckman JF, Swerdlow N, Visser-Vandewalle V, Vitek JL; Tourette Syndrome Association, Inc.
Department of Neurology, University of Rochester, Rochester, New York, USA.
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In response to recent publicity regarding the potential use of deep brain stimulation (DBS) for reducing tic severity in Tourette's syndrome (TS), the Tourette Syndrome Association convened a group of TS and DBS experts to develop recommendations to guide the early use and potential clinical trials of DBS for TS and other tic disorders. The goals of these recommendations are to ensure that all surgical candidates are (1) fully informed about the risks, benefits, and alternative treatments available; (2) receive a comprehensive evaluation before surgery to ensure that DBS is clearly the appropriate clinical treatment choice; and (3) that early clinical experience will be documented publicly to facilitate rational decision-making for both clinical care and future clinical trials.
PMID: 16991144 [PubMed - indexed for MEDLINE]
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