I took Amitriptyline for neck pain but I stopped as it caused weight gain. I think I also tried dopomax or something similar to Amitriptyline for a time as well. Are you taking this for TOS? My past TOS neurologist recommended Topomax. I think I tried it but don't remember details. I have nerve pain with the TOS and Neurontin (gabapentin) and Lyrica have worked best for me. Lyrica so far is the best for the TOS nerve pain for me.