I have twitching, spasms, and Jerks all over......some of it is due to the mestinon, but mostly to my RLS....my doc said that it can move from your legs all the way up your body in severe cases, esp. if you have other issues going on. I am on requip but it doesn't help much. She also said it had alot to do with the ferritin level in your iron. If it is low it can cause your body to spas and jerk. my hands look as though I am going the dts all the time. I can be laying down and my hips will jerk and rotate without me doing it or my leg will just kick out like someone is testing my reflexes. It is crazy....I hope you find a solution. But I hope your doc told you how important it was to cont. the mestinon if you are not in remission. You don't want to go into a crisis.

Wishing you well,

Barb