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Old 09-01-2007, 06:31 AM
glenntaj glenntaj is offline
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glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default There are a lot of causes of muscular fasiculations--

--including neuropathy, of course, though if one experiences it within the context of neuropathy, it would mean that one had at least some motor involvement.

There are a number of people for whom cramping/fasiculation has been the only motor symptom they've experienced. Annoying, but much les debilitating than actual muscle weakness. Such people are usually described as having a sensorimotor neuropathy--the main affected system is mentioned first--and this is actually fairly common. Many of the conditions that can affect myelination--from autoimmune situations to toxins to nutritional deficiencies, can result in this pattern.

And, autonomic disruptions are common, though often subclinical, in any syndrome in which there is substantial small-fiber involvement. Again, one can have a neuropathy with predominantly small-fiber disruption, predominantly large-fiber disruption, or a mixed type. The permutations are many.

Patchy sensory disruption is a bit less common, but does occur. In fact, asymmetric sensory disruption does tend to cause one to lean towards certain diagnoses, especially vasculitic autoimmune conditions, a number of infectious conditions (Lyme, West Nile, Hepatitis C) and, unfortuantely, a number of blood cancers.

See:

http://www.neuro.wustl.edu/neuromusc...symmetric.html
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