Tena - Mirapex worked for my PD symptoms (I am tremor dominant) for the 3 years I took it after I was diagnosed in 1999 (I was 41 years old). It was the only drug I used. It made me sleepy, fogged my brain, and caused OCD behavior, mainly obsessive computer use. Since that was 8 years ago, when it had been out only for a short time, there wasn't as much known about it as there is now - I took it without the knowledge of all of these potential side effects.

I then took Requip alone for 3 more years (I switched because I was falling asleep at the wheel while commuting to my job) before I started Sinemet.

I think it was good to delay the start of Sinemet for me; I would start the same way again, but be really cognizant of the potential downsides of Mirapex - and I would also make sure close family and friends were aware, so that if things begin to go wrong, adjustments can be made. Also, I am now on SSDI and no longer commuting to a job - don't think I could have continued to drive alone for long distances under the influence of any agonist.

It's an effective PD drug that needs to be taken with extreme caution.