My sleepless nights seem to be catching up on me. I am dragging myself around throughout the day and I look like hell. My sleeping habits have never been good but this last few years since dxs is getting worse all the time. I feel so tired but I don't go to sleep and when I do I only sleep for about 2 or 3 hours and then I'm up again. Since visiting my MDS last week I have reduced my Requip to 12 mgs a day from 14 mgs.( I was feeling very restless and not able to sit still) and I take Sinemet 100/25 3 x a day, my Dr. has now added Sinemet CR at bedtime in hopes of some symptom relief which will in turn allow me to sleep. Its been 3 nights since I started the bedtime dose and I am not sleeping any better. Granted it has taken care of my night time dystonia. She says if I still am having trouble sleeping in 2 weeks she will prescribe a low dose of Seroquel. Have any of you tried Seroquel for sleep and how much is considered a low dose.