Dear Birte and Chris,
I started on Amantadine in the early days of PD about 12, 13 yrs ago and found it to be a fairly unremarkable drug in helping what was then, in retrospect fairly mild symptoms.
Now it's the only drug I take. It was recommenced 18 months ago.
No amount of changes in the settings for my neurostimulators seemed to be effective (although everything else is working well now) in helping gait and balance problems but by the third week of introducing what was by then 3 amantadine/ day my gait was fantastic and I haven't felt better in 14 yrs since being diagnosed with P.D.
Robert thankyou for your ideas on how Amantadine may work.
Regards,
Lee