Magnate
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Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
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Magnate
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
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Some forms of autoimmune neuropathy--
--have a stocking-glove distribution, especially if the autoimmune attack is directed at the myelin sheath (as opposed to the nerve fiber, or axon, itself), as this disrupts the signal most towards the endpoints of the nerves.
It's not a hard/fast rule, though. Some autoimmune neuropathies affect the whole body, and don't necessarily start in the feet or hands.
Sjogren's (of course) comes with a full range of distributions. Often, whether one would experience the stocking-love distribution here depends on the site of the nerve attack. If the small fibers are affected primarily, one would expect to have symtpoms first in hands/feet. But Sjogren's is also notable for attacking the dorsal root ganglia (technically, a neuronopathy), which would produce non-length-dependent symptoms that could strike anywhere. People with Sjogren's (unfortunately) sometimes report report symptoms in the peroneal nerve, the trigeminal region, the medial/ulnar nerves of the arms . . .in essence, anywhere in the body there is moisture gland inflammation.
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