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Old 09-19-2007, 12:55 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb allopurinol may be a culprit...

This drug is reported to cause neuropathy.

While it is not common, it can happen:
Quote:
Eur Neurol. 1993;33(3):193-4.Links
Regression of allopurinol-induced peripheral neuropathy after drug withdrawal.
Azulay JP, Blin O, Valentin P, Abegg P, Pellissier JF, Serratrice G.

Clinique des Maladies du Système Nerveux, CHU Timone, Marseille, France.

A patient experienced an axonomyelinic peripheral neuropathy during a long-term allopurinol treatment. The symptoms and signs regressed after drug withdrawal, and the nerve conduction velocities and distal latencies improved. The incidence of allopurinol-induced peripheral neuropathy is very low. Thus, facilitatory factors have to be sought.

PMID: 8385614 [PubMed - indexed for MEDLINE]
There are a few other reports on Medline, but they do not have abstracts I can access.
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