--as regards hyperreflexia, or exaggerated reflex response, it can be a feature of certain types of neuropathy, though more often the reflexes are reduced. It is more likely to occur in neuropathies with significant motor neuron involvement (as opposed to predominantly sensory). It can sometimes occur in those with hyperthyroid or hyperparathyroid conditions.

Hyperreflexia is more often associated with spinal cord problems, and is a fairly common symptom of multiple sclerosis, ALS, or degeneration due to B12 deficiency.