I got so depressed that I had to take something. It does become a matter of life or death sometimes. I was less than flat, I was under...

I've taken Wellbutrin - no side effects at all. Felt like a good night's sleep. Takes a month to work.

Cymbalta - which is supposed to heal the nerves, also help sleep, seemed to gain weight and stop any sex drive - which was gone anyways due to TOS headaches / spasms...takes about 3 weeks to a month to work.

What I know about most antidepressants is that they take a month to build up in your system. During that time you may have headaches, stomach aches and some flu-like symptoms (mild compared to what we deal with) and then upon day 30 they basically vanish and the drug becomes therapeutic. That's not a scientific statement, that's my OWN personal experience and that of my family members.

Antidepressants - generally - can NOT be taken "once" for a day or so...again, it's the level in the blood that must be meant for any effect on your system. (Unlike Xanax or our pain meds.)

And, you can't just quit them. You have to cut them down over a month's period also...

Other people here take Lexipro. Paxil and Zoloft both create weight gain eventually (after six months according to statistics) but help with sleep. Prozac can initially cause a loss of appetite, and is not recommended for anorexics...and I feel after 9 months it just stops working. (Personal opinions mixed in again.) Hope this is helpful, and not meant to offend anyone else's experiences. Each bod is different!!!