With the news that the majority of diabetics are lacking in thiamine, it makes one wonder just how many diabetic neuropathy sufferers have a severe lack of the vitamin . Taking into account that some antihyperglycemic meds also deplete the vitamin , it could be a real " catch 22 " situation. Not just diabetics, but also heavy drinkers suffer a loss of thiamine due to the affects of the alcohol on Thiamine absorption. Symptoms of small fiber polyneuropathy , burning feet and calves , parenthesias..sound familiar? I entered this thread because being newly diagnosed diabetic with a painful neuropathy, I had my Thiamine level checked and low and behold..pretty damn low! So I think I am going to give about 300 mgs a day a try . Does this sound like a pretty good dosage to any of you who are supplementing?..Tom