Cheryl,

Methylcobalamin has been shown helpful to a percentage of people who have problems and cannot be shown B12 deficient, even with proper testing.

Yes, I would take the 5000 mcg and hope. If it is doesn't help directly, at least it won't hurt, and having a good store of B12 is a very good thing for the body.

Many things can interfere with B12 absorption, but I have never seen anything indicating that B12 interferes with meds, etc.

I'm very bad at acronyms . DPN?

rose