Mrs. D, I was recently referred to a doctor who specializes in pain management. He swithced me from the fentanyl patch to methadone to see if methadone would be more helpful to me with pain control. He never asked me if I had any heart problems! Or told me about other drugs to avoid! Sheeeesh. I can see where family docs or internests might not know about these studies, but you would think that a pain doc would. At any rate, the metadone was not as efficacious for me and made me too sleepy. I was hoping it would be because it is so cheap. But now I am glad it wasn't.