Vicc, has a good point about having to take the meds. I would take my Methadone no matter what anyone said to me unless the side effects kept me from doing it. It's a matter of trying to keep the pain level down.

Mike has a good point also about Drs. If your wife has a good Dr. then ask him to do the test when needed to check and see if the meds are affecting her kidneys, liver, or whatever.

Like Mike, I have the best PCP ever and I have a very good Pharmacist so I call Steve if I have some question about meds if I can't get my Dr.

I will say though on the side effects, I do question taking some meds when you see some of those side effects coming out and not going away. Bill was on a med for high blood pressure that I am sure most likely helped kill him. The Drs. would keep putting him right back on it. I could see the side effects from it and they were horrible.

A lot of time the Drs. don't even know all of the side effects due to the pharmaceutical companies leaving them out of the little book the Drs. use. I saw that first hand with Vioxx.

I do think you have a legitimate concern about the meds but my thought would be make sure your Dr. is doing the test needed to make sure she isn't being effected by the meds.

Ada