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Junior Member
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Join Date: Sep 2007
Location: Australia
Posts: 29
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Junior Member
Join Date: Sep 2007
Location: Australia
Posts: 29
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subacute combined systems disease
Hello Everyone:
would it be safe to assume (arghhh.... dangerous I suppose) that IF you have been deficient in B12 for some considerable time (literature says neuro symptoms show before blood work does) that it could have progressed to subacute combined systems disease?
These problems have been slowly accruing for over 7 years that I can definitely remember. I am on PPI and have been for over 7 years, before that other gastric acid reducers for about twenty years, but no one has ever put two and two together........ I mean I am supposing PPI's could be a reason for malabsorbtion or killing off of stomach cells etc?
Reason I ask this is because I have some white matter changes showing in recent MRI's that docs say is DEFINITELY NOT MS, and I have heaps of neuro signs, like tingling/burning legs and feet, arms and hands, light headedness and dizziness, thought problems and remembering problems etc etc etc...... walking is becoming difficult for me too now, my hips are hurting, and xrays show them and knees to be 'normal'.
I am asking you who are more knowledgable to help me out here, give me reading to do, links to follow etc.... where you can.
I am awaiting results of Hcy and MMA..... B12 levels have fallen (in 5 months) from 548 to 362. I have started giving myself IM B12 every other day, when my supply runs out this week I have sublingual methyl 5mg ready to take.
Thanks for considering my question.
Cheer's 
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Cheers from Clare in Tassie
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