I had my first 'pre-filled' Avonex injection last night and have been violently ill since. I used to use the unmixed when it first came out and only had the aches & pains, which was controlled with ibuprofen. I have not been on any CRABS for 3 years as I was doing 'N', but have finished that now and the neuro wanted me back on CRABS.

I don't know if the violent vomitting was due to the new pre-mixed formula, or the fact that I've been off the CRABS so long. In any case, this has been the worst reaction I've had, I hope I haven't built up an allergy, if I'm this sick again next week, I'm going to ask for the old 'mix'!

I would be interested to hear how you go with the pre-mixed, or if anyone else has been violently ill after using the pre-mixed.