Hi Penny,

Just thought I would weigh in my two cents and say I had no trouble what so ever with the switch to the prefilled.

A better idea is to call the Avonex hot line and maybe get some statistics on what % of people can't tolerate the prefilled variety after switching.

I really like the prefilled, I generally don't like people messing with things I am comfortable with. I actually dreaded switching, but in the end it was no big deal and I do like it alot better.

I sure the other posters had problems, but they only represent a sample of those people on this forum who take Avonex. Maybe there aren't that many of us Avonex users on this forum. I really don't know. Anyway you could try it one week and and switch back if you don't do well.

Hope you do well no matter what.