--and he certainly has first hand experience in this realm.

There is increasing evidence that high insulin levels, especially as revealed during glucose challenge, may well be the first step on the path to diabetes, but that one can get neuropathic symptoms--especially small-fiber sensory ones--well before a frank diagnosis of diabetes can be made, when one is in the realm of "impaired glucose tolerance". And subtle abnormalities of glucose/insulin relationship may not be observable except through such extended glucose tolerance testing (in other words, your "fasting" glucsoe levels and hemoglobin A1c readings may be nicely in range, and you can still have a problem).

High insulin levels (that are not caused by insulinoma, which is very rare) are usually due to insulin resistance--the body's cells have become inured to its actions, meaning much more must be produced to get glucose into cells past resisting cell walls so as to keep blood glucose within tolerable levels. Without dietary and/or exercise intervention, resistance often will increase until the glucose levels can no longer be kept within non-diabetic ranges.

Here are some papers that talk about pre-diabetic neuropathy (so you can show the nuero):


http://www.massgeneral.org/neurology...dOaklander.pdf

http://appneurology.com/showArticle....leId=188500771

http://care.diabetesjournals.org/cgi...full/24/8/1448

http://www.neurology.org/cgi/content/abstract/57/9/1701

http://www.medpagetoday.com/Neurolog...rology/tb/3538