Hi Mike,
this certainly is interesting & although I have read many times as also stated in this article that topical application of capsaicin is an extreme irritant to some rsd sufferers, this is certainly promising.
Basically, I see it as a potential quantum leap in the right direction: almost an active vector that goes beyond the role of a catalyst & vector & plays a role in moderating the affected cell......wow!
This combination might just carry it deep enough (just ever so sub-Q) to help as a cream. Other more efficacious methods of admin could increase drug efficacy too. This sort of work sets the mind racing in a positive way.
The mind boggles to the heddy heights of drug delivery by nonobes...now that would be something.
Complementary polypharmacy with targeting nanobes...who would have thought?
Mssrs Woolf & Bean certainly have a good rep.
This I will watch closely.
Thanks heaps for the post.
Auberon