Not a 'roid rage? Steroids are tough!
I have no problem with Singulair...nada. I have been able to be almost 100% inhaler free... excluding environmental insults that are unforeseen.
Here is the reported side effect list:
http://www.rxlist.com/cgi/generic/monteluk_ad.htm
It is one of the most mild tables of side effects I have ever seen.
Singulair metabolites are excreted thru the gall bladder. That is the only major factor I would consider, in those with biliary cirrhosis, which is not common.
Some small children exhibit irritable behavior with allergies, and hence on Singulair. But it is not common either. In general people who are sick are easily irritable and it is very hard to prove it is the drug causing it.
This means it does not cross the blood brain barrier..
Quote:
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Montelukast is more than 99% bound to plasma proteins. The steady state volume of distribution of montelukast averages 8 to 11 liters. Studies in rats with radiolabeled montelukast indicate minimal distribution across the blood-brain barrier. In addition, concentrations of radiolabeled material at 24 hours postdose were minimal in all other tissues
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So one would not expect much in the way of psychiatric side effects.
Here is the FDA reports (623 compared to 2100+ for forteo which is not nearly used as much)
The most common appear to be in small children, and convulsive.
Steroids are really really hard on the body. They create huge problems in comparison. So I hope you will give it a try at least. If it does not work for you, then at least you will know that.
edit to add: Small children and the very old, often have blood brain barrier faults. For example, Zantac and Pepcid can cause
delirium in the very old, while not causing this in other age groups. When the blood brain barrier fails many drugs and viruses and bacteria and peptides from food, can enter.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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