cadsil disease, a leukodystrophy, is a genetic disease involving the destruction of microscopic vessels deep in the brain. A genetic defect causes the vessel walls to lose integrity and the result is multiple strokes and a lot of brain damage. An MRI does not show the vessel damage, tho, so I don't know what they saw.Cadasil damages can be best seen by an electron microscope at autopsy. The disease is best Dxd by a genetic test. Cadsil is rare affecting 400 families world wide and sysmptoms are migranes and strokes. if you search for "vascular dementia" diseases, I think you'll have better luck getting good information. Good luck.