Glad to hear some respone about the patches, I was taking narcotic's for work related pain but working in a paint dept got me so buzzed-up my PM gave me these. I used them for 2 years steady at work to get my retirement in, now I cut back on them. Had a flare up in the groin lately and started using them again, hurts more to take them off in that area doe-ha! I was told there made from the coca plant, cocaine, they take the coca out to make the patch. That's just what I was told, maybe a Doc would know more, but if you go for a drug test u better tell them your using them. Best