Dear Frogga -

I have requested this article from my friend who has access to such things:

"Neurokinin mediation of edema and inflammation," Campos MM, Calixto JB, Neuropeptides 2000 Oct; 34(5):314-22.

The aim of this article is to furnish a brief review of the role played by neurokinins in the inflammatory process. Further attention is given to the mechanisms, as well as to the receptor subtypes involved in neurokinin-mediated inflammation, in an attempt to clarify the participation of neurokinins in different models of acute and chronic inflammation. The involvement of SP, NKA and NKB is also examined in relation to the major signs of inflammation, including edema formation, protein plasma extravasation and vasodilatation. Finally, we provide a general overview on the potential clinical applications of neurokinin antagonists, along with the involvement of neurokinins in human diseases.

It sounds interesting. Edema - or oedema for our friends in the Commonweath - obviously ties into an inflammatory process, it would just be nice to understand the mechanism in a little more detail. I'll make the article available, when and as it falls into my hands.

Mike