The study used a nanoparticle formulation. If you can find that, then it seems 300 mg a day is enough.
Preparation and Characterization of Novel Coenzyme Q 10 Nanoparticles Engineered from Microemulsion … -
http://www.aapspharmscitech.org/arti...2/pt040332.pdf
There's a Japanese formulation that I think is available as Q-sorb, but I don't know if it's the same. I purchased some by Nature's Bounty at CVS, buy one, get one free.
Darn....
Journal of Medicinal Food
A New Coenzyme Q10 Tablet-Grade Formulation (all-Q®) Is Bioequivalent to Q-Gel® and Both Have Better Bioavailability Properties than Q-SorB®
To cite this paper:
U. Ullmann, J. Metzner, C. Schulz, J. Perkins, B. Leuenberger. Journal of Medicinal Food. 2005, 8(3): 397-399. doi:10.1089/jmf.2005.8.397.
U. Ullmann
R&D Human Nutrition & Health, DSM Nutritional Products Ltd., Kaiseraugst, Switzerland.
J. Metzner
GALMED Institute for Galenic & Medicine Research, Halle/Saale.
C. Schulz
BIOTESYS GmbH, Esslingen, Germany.
J. Perkins
R&D Human Nutrition & Health, DSM Nutritional Products Ltd., Kaiseraugst, Switzerland.
B. Leuenberger
R&D Human Nutrition & Health, DSM Nutritional Products Ltd., Kaiseraugst, Switzerland.
Commercial Coenzyme Q10 (CoQ10, ubiquinone) formulations are often of poor intestinal absorption. We investigated the bioavailability of DSM Nutritional Products Ltd. (Kaiseraugst, Switzerland) CoQ10 10% TG/P (all-Q®), a new tablet-grade formulation, with CoQ10 Q-Gel® Softsules® based on the Bio-Solv® technology (Tishcon Corp., Salisbury, MD; marketed by Epic4Health™, Smithtown, NY) and Q-SorB® (Nature's Bounty™, Bohemia, NY). Twelve healthy male subjects participated in a randomized, three-period crossover bioequivalence study. Plasma CoQ10 was determined from pre-dose until +36 hours. To compare bioavailability, corrected maximum concentration (C max) and area under the curve from 0 to +14 hours [AUC(0-14 h)] were assessed and tested for bioequivalence. The bioequivalence ranges of 0.8–1.25 hour × µg/mL for AUC(0-14 h) and 0.75–1.33 µg/mL for C max were applied. In summary, the kinetic profiles of all CoQ10 preparations revealed a one-peak plasma concentration–time course. Highest C max values were seen after Q-Gel application, whereas time to C max was nearly identical across all treatments. The AUC(0-14 h) values were highest for Q-Gel, narrowly followed by all-Q. The tests for bioequivalence showed a bioequivalence between Q-Gel and all-Q, and both preparations were found to have better bioavailability properties than Q-SorB. Although all-Q and Q-Gel have equivalent bioavailability properties, all-Q can be directly used in tablets, while this is not the case for Q-Gel or other similar forms.
http://www.qgel.com/
http://www.swansonvitamins.com/webap...urlID=31363043