I am convinced that nicotine is one of the reasons I don't have Parkinson's right now. (http://www.lindborglabs.com/AboutHeid.htm)

And as a long time user, I have to say that the experiment using 35mg patches over 12 hours most likely overdosed the patients. I've been smoking a pack a day for 30 years and I couldn't have handled that high a dose. When I use patches (I have to when I visit my mother) I get the 21mg and cut it in half and take it off after dinner. I will be interested to see the new study and if they did dosage dependent analysis.