No doubt about THAT.

Finding ways to adapt and cope, I think will vary from person to person.

You want to make sure Billye that you are getting enough folic acid
to compensate for the methotrexate. If you happen to be one of the
part of the population that does not activate/methylate folic acid properly,
you won't see its benefits.

In that case you need folinic acid...available by Source Naturals, or RX version from your doctor..Leucovorin.
Metanx RX is the only version of methylfolate you can get now. Merck stopped selling it OTC. You might ask your doctor for it, if you have insurance.
Metanx has methylB12, methylfolate and P-5-p-- activated pyridoxine.
B6 is essential for making serotonin..the antidepression neurotransmitter.

Sometimes we make assumptions that something is working, when it is not.
There are 25 genetic errors in folate chemistry, and I expect they will find more. So if one folic acid doesn't work, I think you should give another a try.
Low folate causes depression, with that increased pain levels.

I am so sorry you are feeling so down. Down I understand personally, and I have been on my visor now for two weeks as a matter of fact.
I hope your increased pain levels don't last much longer.