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Old 10-28-2007, 03:56 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb I found...

studies showing low dose does not affect the methotrexate. High dose can.

When leucovorin is used orally, RX, the minimal dose begins at 5mg.
The OTC one starts at 800mcg (which is less than 1mg).

And remember...if you have a MTHR polymorphism...and cannot convert folic acid
it won't work at all. There are 25 different genetic errors so far discovered. And this
is separate from the methotrexate data.
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