for providing your dosing schedule for Amantadine...and, too, for your encouraging words about Amantadine itself...exactly what Doreen and I need at this time.

Just another question, John...what is your Sinemet dosage, i.e., how much at each of the 4 dosings? Doreen has been taking the Sinemet 3 times daily...25/100 mg...1 1/2 @ 7 a.m.....1 1/2 - 2 @ 11 a.m. (depending on how well it "works" at this time)...2 @ approx. 4 p.m. w/ a possible total of 5 1/2 tabs daily. Until very recently, she had only been taking 4 tabs a day divided by 3 doses= 1 1/2 + 1 1/2 +1= 4 tabs...but, now at the 5 - 5 1/2 tabs. I have suggested to her that possibly she should be taking smaller doses more frequently but equaling the same total amount of 5 - 5 1/2 tabs...possibly even using a 4-dose daily regimen as you do. I guess my thinking on this is that she might be insured of a more constant "flow"of the Sinemet w/out the more concentrated dose at fewer intervals. The more recent increase in the Sinemet has NOT resulted in the dyskinesia(s) that she had been experiencing before adding the Amantadine so that we're hoping that the increased amount of the Sinemet will help with the tremor, and in fact, her neurologist told her today that she can even take 6 Sinemet daily to see if that would give an even better benefit toward controlling the tremor...but, he still feels that he would like to increase the Amantadine to see if that "works" well to control the tremor. I guess, though, he will wait to see if the increased Sinemet dosage helps with the tremor..if so, then, there would be no need to increase the Amantadine to 300 mg. daily...if not, then, he may decrease the Sinemet and have Doreen "move to" the 300 mg. Amantadine. He likes to "work" with one "med" at a time so that it's clear as to what "med" is doing (or not doing) what.

Gosh, John...I have rattled on, here...really went quite astray from my original question to you, i.e., what are your Sinemet doses, i.e., total daily dosage and how much at each dosing? Also, does the amount of Sinemet control your tremor well...or, is it possibly the Amantadine that is contributing to control of your tremor? Believe me...if you can make "heads nor tails" out of this, it will be a miracle!!!! I tend to write as I am thinking and I just have so many thoughts. It's a wonder that anyone would take the time to "wade" through some (probably most) of my posts!!!

Thanks, again...
Therese