View Single Post
Old 10-29-2007, 06:51 PM
RLSmi's Avatar
RLSmi RLSmi is offline
Member
 
Join Date: Oct 2006
Location: dx'd4/01@63 Louisiana
Posts: 562
15 yr Member
RLSmi RLSmi is offline
Member
RLSmi's Avatar
 
Join Date: Oct 2006
Location: dx'd4/01@63 Louisiana
Posts: 562
15 yr Member
Default Is it just a coincidence?

The following will only make sense to forum members who know about my use of DM (dextromethorphan) in an attempt at neuroprotection of my remaining mid-brain neurons.

AshleyK and others recognize that this is something I began four or five years ago after learning that a similar drug, naltrexone, appeared to have neuroprotective effects when taken at very low doses.

I was propelled into this experiment after learning about research work done in the laboratories of Dr. J-S. Hong at the NIEH (National Institute of Environmental Health) at Research Triangle, North Carolina. He found that both naltrexone and dextromethorphan, as well as naloxone and the endogenous peptide dynorphin, decreased the inflamatory activation of microglial cells in animal mid-brains at extremely low concentrations. I began taking low doses of DM since it could be obtained in simple cough syrups without a prescription, unlike the other drugs.

Maybe I should use the "paranoid" mood tag like Carolyn, but the sudden recommendations from (?) to remove cough remedies for children from the pharmacy shelves "because they are ineffective, or may be harmful" just happen to be the precise OTC medications I have been using to get my dextromethorphan. I use the pediatric preparations containing the lowest concentration of DM because that makes it is easier to measure the very small 4-6 mg dose I take each night (slightly over 1/2 teaspoon of syrup with 7.5 mg per teaspoon). Curiously, those are also the only DM preparations in which it is the only active ingredient. The closest I have been able to come lately are preparations which also contain an antihistamine.

Have the FDA and/or their Big Pharma buddies found out about the potential for neuroprotection by this class of drugs and they don't want the word to get out so Drugs Inc. can make a "me too" drug and market it as a blockbuster?

I told you I was paranoid!
RLSmi is offline   Reply With QuoteReply With Quote