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Old 10-29-2007, 07:21 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Red face this is beyond me...

so I went looking for you.

http://content.nejm.org/cgi/content/extract/353/6/634
So that article says they do not agree with Dr. Licata (who works for Lilly)

Here is Dr. Licata's take from Medscape:
Quote:
Calcium and vitamin D in patients on teriparatide for osteoporosis

Zosia Chustecka
Information from Industry
Assess clinically focused product information on Medscape.

* Click Here for Product Infosites -- Information from Industry.


May 4, 2005

Cleveland, OH - In clinical practice, the doses for calcium and vitamin-D supplements that are recommended by national guidelines for use in osteoporosis may be too high for patients who are undergoing treatment with the parathyroid hormone teriparatide (Forteo, Lilly) [1]. Having found persistent hypercalcemia developing in several patients on this drug, Dr Angelo Licata (Cleveland Clinic, OH) now limits the use of these supplements and suggests that other physicians do likewise.

Writing in a letter in the May 5, 2005 issue of the New England Journal of Medicine, Licata explains that when starting teriparatide therapy he now maintains patients on daily elemental calcium at 1000 mg or less to keep the serum level of calcium below 10 mg/dL and does not give supplemental vitamin D at all if the basal level is greater than 20 ng/mL. "This approach may be useful for practitioners as a way to prevent hypercalcemia in clinical practice," he says.

The recommendation is made after close surveillance of 12 patients, which was prompted by a finding of persistent hypercalcemia (serum calcium levels of 11-11.5 mg/dL) in 3 patients during initial use of teriparatide. In addition to this drug, all 12 patients were taking calcium (mean daily dose 1100 mg), and 10 patients were also taking vitamin D (mean daily dose 355+200 IU). During the first 3 months of treatment, there was a decrease in the levels of intact parathyroid hormone and in levels of 25-hydroxyvitamin D and an increase in the levels of total serum calcium and 1,25-dihydroxyvitamin D.

The fact there was a substantial rise in serum 1,25-dihydroxyvitamin D levels in the presence of decreased levels of intact parathyroid hormone and increased levels of calcium suggests that teriparatide affects the serum concentration of vitamin D even in the presence of physiological signals that normally decrease its concentration, says Licata.


Licata has served as a clinical investigator for Lilly and NPS Pharmaceuticals and has received lecturer fees from Lilly.
So you see, the problem? No one agrees on what to do. I don't trust anyone who works for Lilly...that is my opinion however. They don't have a good track record for honesty.

Here is a post at Healthboards...where a gal took Vit D and Forteo together..
http://www.healthboards.com/boards/s...=427963&page=2
Page 1 about Forteo:
http://www.healthboards.com/boards/s...+D+with+Forteo

http://osteoporosis.emedtv.com/forteo/forteo.html
Looks like you need to call your doctor back and get exact directions.

I am not going to make any recommendations, because this is beyond me,
and my experience.
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