my neuro told me studies had been done and found that wellbutrin had no impact on pd symptoms, and eventually, because i was going to try rasagiline, she put her foot down and commanded me to go down from 450mg/day to 300mg/day (she had been trying to get me to go down for some time - "why," i asked, "because 450 is a lot," she would say,"yeah, and?" i would say, "no adverse effects, doing fine, staying at 450.")

so i went down to 300 and my symptoms tanked. brand new pair of really nice shoes looked like the toes had been stuck into a shredder within a month. i could barely type most days. ended up not trying the rasagiline and eventually going back to 450, et voila, typing was good again most days, walking was vastly improved.... am hitting some kind of rough spot at the moment but overall, the wellbutrin mirapex combo has worked well for me.

oh and controlled release version seemed to make my thinking muddy - i take the original formulation.