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In Remembrance
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Join Date: Aug 2006
Posts: 3,772
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In Remembrance
Join Date: Aug 2006
Posts: 3,772
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boy, was this rich
1: Clin Neuropharmacol. 1985;8(4):318-27.
Sinemet "abusers".
Nausieda PA.
It is generally assumed that parkinsonian patients perceive their need for
antiparkinsonian drugs on the basis of emergent motor symptoms. We describe five
patients in whom an apparent psychologic effect from levodopa prompted dosage
escalation to the point of toxicity. Abstinence from dopaminergic drugs resulted
in the appearance of drug-seeking behavior. Psychologic dependence on levodopa
has not previously been reported, but appears to occur in a small subset of
parkinsonian patients.
"emergent" symptoms?? as in "you should have taken it 30 minutes ago?"
escalation is pretty darned easy when the target symptoms are the same as overdose
Sheesh...
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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