Has been used in very high doses for Friedrich's Ataxia and Parkinson's.

Where there may be mitochondrial damage, CoQ-10 may help.
The mitochondria are the energy parts of each cell. And some attention is
being paid to recessive holders of mito genes that are disabling.
One theory is that 2 genes gives serious disease, present from birth.
And that one gene does cause problems in later life. This has not been
proven yet, that I have seen.

If one takes statin drugs for cholesterol you must have CoQ-10 because those drugs destroy your body's ability to make it, for yourself.

Good CoQ-10 products are expensive, but not dangeous to use. So if you want to try them, pick a quality one with information on the label indicating
Q-sorb or other similar names --a softgel type, not a powder.
If you go to www.epic4health.com there are some explanations as to
what constitutes a quality type.

Some of the drugs that deplete or impair CoQ-10 are:
beta blockers
thiazide diuretics
hydralazine
phenothiazines (Thorazine etc)
TCAs (amitriptyline etc)
some anti-diabetic drugs (glipizide, glyburide)
methyldopa
statins for cholesterol (pravastatin, Lipitor, Zocor etc)