In the paper above on "chronic fatigue syndrome," you can substitute PD for CFS totally, and you get exactly what I have been proposing for PD. Fatigue is commonly associated with PD, does this mean that we all have CFS as well as PD???
However, this set me thinking (again)!
No-one would listen to BArry Marshall's assertions on helicobacter pilori and ulcers, so he infected himself with HP, got ulcers then erradicated the HP with antibiotics. Then they listened and gave him the Nobel prize!!
So what if we find a volunteer, give him some of the substances in the CSF reference above that damages the BBB, and show that he gets PD!!!
Then all we have to do to cure him, is find out how to repair his BBB such that the permeability is back to that of a healthy person. Easy Eh....
Ron