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Old 11-12-2007, 06:55 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Post Pcos...

is complex. There is a PCOS board I'd suggest you visit.

Acne from PCOS is typically due to imbalance of hormones and androgen.
http://forums.obgyn.net/pcos/
The forum there is a little hard to navigate, but there are many responses there that discuss the various treatment interventions.

I had PCOS, and it affected my ability to have children. I managed one
pregnancy, and this was before PCOS was understood. I never had acne from it, but I did have other problems.
PCOS is a somewhat beyond this board. There are many other good sites on
the net if you google it.

I think you need a good endocrinologist (hormone specialist) with the complex effects that Prednisone caused for you.

Flax oil, and evening primrose may help with the acne. Low EFA status is typically common in acne. Low Folic acid and zinc as well.
I would caution you against retinol drugs as treatment. They work on the acne but disrupt your EFA metabolism terribly. The tradeoff is worse than with Prednisone. Triglycerides go dangerously high, and the brain is depleted of DHA which is a vital EFA, and depression results. Accutane in USA it is called and has been under scrutiny for years here. It is a very dangerous drug IMO.
This is a list of side effects possible for Accutane (retinol)
Quote:
Isotretinoin (Accutane)

Primary Use: Treatment of cystic acne, psoriasis and various skin disorders.

Certain side effects:
Abnormal meibomian gland secretion
Meibomian gland atrophy
Blepharoconjunctivitis
Myopia
Corneal opacities
Ocular discomfort
Decreased dark adaptation
Ocular sicca
Decreased tolerance to contact lens
Photophobia.
Decreased vision
Increased tear osmolarity
Teratogenic ocular abnormalities
Keratitis
Teratogenic ocular abnormalities

Probable/likely side effetcs:
Decreased color vision (reversible)
Permanent loss of dark adaptation
Pseudotumor cerebri

Possible side effects:
Corneal ulcers
Optic neuritis
Diplopia
Permanent sicca-like syndrome
Eyelid edema
Subconjunctival hemorrhage
Idiopathic intracranial hypertension with optic disk edema

Unlikely side effects:
Activation of herpes simplex virus
Keratoconus
Corneal vascularization
Limbal infiltrates
Exophthalmos
Pupil abnormalities
Glaucoma
Vitreous disturbance

Conditional/Unclassifiable side effects:
Cataracts
Peripheral field loss
Cortical blindness
Retinal findings
Decreased accommodation
Scleritis
Iritis
It can cause Guillain-Barre syndrome and neuropathy:
http://www.bmj.com/cgi/content/full/328/7455/1537

This drug affects fat metabolism, and destroys nerve sheaths esp in the eye, but also elsewhere in the brain.
I'd stay away from it, as you already have nerve problems.
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