Thread: BBB update
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Old 11-21-2007, 06:08 PM
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reverett123 reverett123 is offline
In Remembrance
  
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default While a bit technical...
There is a good bit of info on the BBB transport systems at http://jn.nutrition.org/cgi/content/...ct/130/4/1016S
Note that the full text is free too.

One problem not addressed in the BBB idea is the work by Kraak showing transport inside the neurons themselves from nose and stomach. Such movement would presumably bypass the BBB altogether.

I think we make a fundamental mistake when we assume that there is a single cause for PD. It is quite possible that several factors exist that could combine in different configurations to produce similar results. This could account for the "alike yet different" nature of our common curse.

Finally, in terms of explaining the observed data, this does a decent job
http://neurotalk.psychcentral.com/sh...ght=endotoxins
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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