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Old 11-28-2007, 11:45 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Post bumping up...new study published...

I found this new study on PubMed recently...and it is time to bump up this thread anyway

Quote:
Vopr Pitan. 2007;76(5):67-73.Links
[Study of anti-inflammatory activity of some organic and inorganic magnesium salts in rats fed with magnesium-deficient diet]
[Article in Russian]

[No authors listed]

The purpose of the present research was comparative study of anti-inflammatory action of some Mg salts in rats fed with Mg-deficient diet. It was shown in our study that administration of Mg L-aspartate with pyridoxine leads to higher compensation of Mg deficiency in rats with diet-induced Mg depletion as compared with other Mg supplementations. According to the Mg deficiency correction rate Mg salts may be ranged in the following order: Mg L-aspartate with pyridoxine > or = Mg chloride with pyridoxine > or = Mg lactate with pyridoxine > or = Mg L-aspartate > Mg chloride > Mg orotate. In our study administration of Mg salts resulted in decreased number of blood leukocytes, reduced peripheral vasodilation visible in the external ear, decreased spleen weight, and as consequences in reduced inflammatory and immunological response. According to correction rate of the inflammatory response Mg salts may be ranged in the following order: Mg orotate > or = Mg chloride > or = Mg chloride with pyridoxine > or = Mg L-aspartate > or = MgL-aspartate with pyridoxine > or = Mg lactate with pyridoxine.

PMID: 18030818 [PubMed - in process]
I found this interesting...but not unexpected. Magnesium + pyridoxine are both necessary for the proper conversion of essential fatty acids to long chain ones EPA and DHA. EPA then has anti-inflammatory effects on the body.

For humans I would not be keen on using aspartate salts. Aspartic acid is a neuroexcitatory amino acid like glutamate, and can raise pain levels. I don't know if that is true for rats. But the use of B6 with magnesium is common in many supplements.
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