I start my day with carbidopa/levodopa about 7:30. I'm usually too stiff to do much till that goes to work. Then I take another dose a few hours later. I do have a tendency to get tired after the first dose and want another hour or two of sleep. About a month ago, I started taking Wellbutrin 150 XL with the first dose of carbidopa/levodopa. That has reduced the drowsiness. I haven't noticed that sleeping after the first dose has any diminishing effect on the potency of the drug. If anything, sleeping until it takes effect makes me feel better. But then again, it seems I can never get too much sleep.

Taking a dose of carbidopa/levodopa at night with my clonazepam also helps me sleep. Without it, the rigidity and joint pain keeps me from sleeping. The clonazepam stops the tremors pretty well, but doesn't help with the other symptoms. The two together have worked well for me so far.