It can be hard to separate the effects of the drugs from the effects of the disease. I didn't mean to trouble you and stress can cause a worsening of symptoms. I take gabapentin and this drug severely impedes my ability to see connections between barely related events and wierd coincidences. I don't notice when I take it but when I stop these things will come flooding back. Don't get me wrong, my whole life is like one big Twilight Zone episode with few voice overs by Serling and the music's always playing, but it's moreso without the gabapentin. I kindda miss it.

It's similar with some of the other drugs. Tizanidine eases the tremors but probably affects my thinking. Depakote reduces my ability to obsess which I also miss a little. Fortunately it's primary effect seems to be as an analgesic for me.

But there are numerous things that make this seem like an infection. When in the hospital for a probably related problem they were pumping me full of powerful antibiotics. At the time it felt like the RSD was trying to go away! It came right back when the drugs stopped. A lot of the sensation that it's infection is the two way communication type events. At one point it seemed like the amygdala was involved but this didn't last long. I often felt like I was in a sort of fugue state at the time. It seemed like I operated my legs to cause the world to walk by.

It does seem that this thing prefers other nerve fiber than brain though. Like I say this is just the sensations I get and I'm sure a doctor would use other terms to describe it. Even were I entirely correct it's probably more important to not worry about it than to understand it. I still have a lot of trouble concentrating because the pain starts up if I don't pay attention to it and comes flooding back when I quit. It's no real problem though, I just break stuff up into smaller increments.

My best bet seems to be to just try to stay on top of the triggers and to try to keep stress low.